date:Jan 27, 2014
altered insulin signalling in this brain circuit. As a result, the offspring remained overweight and had abnormalities in glucose metabolism throughout their adult life.
Our study not only shows that the lactation period in rodents is most sensitive to the altered developmental environment in response to maternal HFD feeding, predisposing the offspring for metabolic diseases as described before, but importantly demonstrates that the short exposure to HFD during this distinct developmental phas