date:Jul 14, 2012
acute reference dose (ARfD) for chlorpyrifos in the EU was established in 2005, before much of the recent research on the insecticide was carried out. The current acute reference dose is 0.1mg/kg, on the basis of a NOAEL of 10mg/kg from acute and delayed neurotoxicity studies in rats as a point of departure.
Chronic human risk assessment
In 2005, upon the basis of work done by the European Food Safety Authority (EFSA), the EU also established an acceptable daily intake (ADI) level of 0.01mg/kg